Research reviews revealed that irisin hormone was discovered in 2012, when researchers at Harvard Medical School found that both mice and human could produce the hormone during exercise. Further studies revealed that, in mice, irisin improved blood-sugar regulation and led to weight loss, causing some people to speculate that a drug based on the hormone could be used as a treatment in obesity. This study was, therefore, undertaken to find out the impact of the training of yogic exercises on irisin hormone in obese people. Thirty obese female (n=60), age: 40-50 yrs., from different nearby housing societies in Pune (India), were randomly divided in to two groups viz., 30 experimental and 30 control. The obese subjects were selected on the basis of their BMI (Body Mass Index). Blood sample of these 60 subjects were collected during pre-test, post-test and follow up test to assess the level of irisin hormone by employing Elisa Reader instrument. Yogic exercise training was imparted to the experimental group for a period of 6 months, whereas the controlled subjects did not participate in the said programme. The result of post t-test revealed that the yogic exercise training was significantly effective in increasing the level of irisin hormone (t=3.69, p<0.05) than the control group. This result, in turn, suggests that yogic exercise programme increases irisin hormone that might have helped for weight loss among the female obese.