Published Paper


T-Cell Lymphoma after Silicon Injection in the Eyelids: Rare Case

Raudatul Janah1, Dita Irmaya2
Indonesia
Page: 1579-1586
Published on: 2024 June

Abstract

Background: Lymphoma in the eye can affect the eyeball, orbit, tear glands, and eyelids. The involvement of lymphoma in the eyelids is about 5-20%, usually in the form of non-Hodgkin's lymphoma of 80% B lymphocytes, 14% T lymphocytes, and 6% NK cells. Generally, these lymphomas are unilateral and only 20% of cases are bilateral. In Indonesia, there are no reports of T-cell lymphoma in the eyelids. It is difficult to make an exact diagnosis of T cell lymphoma in the eyelids because it sometimes resembles an inflammation so it requires histopathological and immunohistochemical examination so that the therapy given will be more appropriate. Case: A 50-year-old woman with complaints of lumps on the left and right upper eyelids that have been getting bigger and bigger since 1 year ago. Initially, a lump on the left eyelid followed by a lump on the right eyelid. The patient with a history of using silicon several years ago was initially suspected of having silicone, then underwent surgery in 2018 with reactive hyperplasia results, then in 2019 the operation was carried out again with the results of low-grade non-Hodgkin malignant lymphoma, then continued with immunohistochemical examination with the results of T cell lymphoma eyelid region. Conclusion:Histopathological examination is sometimes difficult to distinguish between reactive hyperplasia and malignant lymphoma. This is because the picture is not typical so further examination with immunohistochemistry is needed for diagnosis using CD 20, CD 3 and ki67.

 

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