Abstract: Introduction: Dental extraction is a routine procedure, with immediate post-extraction healing crucial for preventing complications. However, conditions like diabetes can impair this process due to microcirculatory deficiencies. Platelet-rich fibrin (PRF) is gaining attention for its regenerative properties. This study aims to assess PRF's impact on extraction socket healing in diabetic patients. Materials and Methods: A randomized controlled trial was conducted on 20 diabetic patients requiring multiple extractions. PRF was placed in one socket (experimental) while the control remained untreated. Parameters including tissue color, bleeding, granulation tissue, and pain were evaluated at 1st, 7th, and 21st days post-extraction. Results: Patients exhibited varied glycemic control (110-200 mg/dl). Initial healing was satisfactory, with no major complications. By the 3rdweek, 50% achieved complete socket closure. PRF-treated sockets showed significant improvement in tissue color, bleeding, and granulation tissue compared to controls. Suture margin dehiscence and suppuration were notably reduced in PRF-treated sockets. Pain levels were comparable between groups. Discussion: Previous studies yielded conflicting results on diabetic wound healing. However, PRF's potential in promoting tissue repair has been recognized. PRF, with its ease of preparation and application, offers advantages over other platelet concentrates. This study contributes to existing knowledge by assessing both soft and hard tissue healing over an extended follow-up period. Conclusion: PRF application in extraction sockets of diabetic patients significantly improves soft tissue healing compared to untreated sockets. Pain levels remained similar between groups. These findings advocate for the routine use of PRF in diabetic patients undergoing tooth extraction, offering potential benefits for overall healing outcomes.