Background & Objective : Coronavirus disease 2019 (COVID-19) may increase the risk of acute ischemic stroke similar to the increased risk of 3.2-fold to 7.8-fold seen within the first 3 days after other respiratory tract infections. The purpose of the study is to study the association of COVID 19 and stroke subtypes in patient presenting with acute neurologic symptoms. Materials and Methods : This study was designed as an Observational case control study from January 2021 to March 2022. Demographic data, COVID-19 status, stroke-related risk factors, and clinical and imaging findings pertaining to stroke were collected. Univariate and multivariate analyses were conducted to evaluate the association between COVID-19 and stroke subtypes., Results : In the COVID-19 group, the NIH stroke scale score was found as 9.2 and in the control group the score was found as 7.9. The diagnostic variables such as acute ischemic infract, large vessel occlusions, Middle cerebral artery segments M1 and M2, Anterior cerebral artery segments A1 and A2, and Posterior cerebral artery segments P1 and P2 were evaluated. Out of the 50 patients included in the study, 23 patients (46%) had acute ischemic infract, followed by large vessel occlusions with 10 patients (40%), Anterior cerebral artery segments A1 and A2 with 3 patients (6%) and both Middle cerebral artery segments M1 and M2 as well as Posterior cerebral artery segments P1 and P2 with 2 patients each (4% each).Interpretation and Conclusions: COVID-19 is associated with LVO strokes but not with SVO strokes. Patients with COVID-19 presenting with acute neurologic symptoms warrant a lower threshold for suspicion of large vessel stroke, and prompt workup for large vessel stroke is recommended.