The severity of the impacts of climate change on human comfort depends upon his indoor and outdoor environment. Climate change impacts on air quality, human comfort and health. The window is an important component for a natural ventilation cooling strategy, which can control the air flow between indoors and outdoors. Good indoor air quality is important to achieve indoor comfort and health. Opening a window is the simplest way to improve indoor air quality. It is an important environmental factor that can affect occupants satisfaction and also have great potential for energy saving. The discomfort of indoor environmental condition in occupied spaces in office building has escalated due to combined effect of high solar radiation and humidity levels which is an impact from climate change. This paper reports on the investigation using questionnaire and physical measurement to analyse the adaptation to climate change impacts by occupant through window control. The Analysis of Variance (ANOVA) test conducted at 95% confidence level showed that there was significant statistical difference between the adaptation to climate change impacts and occupant window control. The result shows that occupant windows control and adaptation is a significant adjustment method that can help occupant re-establish their comfort and reduce energy consumption especially in offices. Recommendations were made for occupants to have direct control on the indoor environment, especially by controlling the windows.