Published Paper


Dyslipidemia and its Correlation with Glycated Hemoglobin Levels in Type 2 Diabetes Mellitus: Unraveling the Intricate Relationship for Comprehensive Patient Management

Vikas Tiwari, Abhishek Sharma, Jaishree Karnwal Tiwari, Mohd Afzal, Khushi,
India
Page: 204-217
Published on: 2024 March

Abstract

Background: Diabetes Mellitus features chronic hyperglycemia from insulin secretion or action defects, often leading to dyslipidemia. Type 2 diabetes sufferers are prone to dyslipidemia, a key cardiovascular risk. Glycated hemoglobin reflects glycemic control, disease progression, and complications in diabetes patients. Aim of the study: To evaluate the level of HbA1c and lipid profile in type 2 diabetes patients & find out the correlation between HbA1c and lipid profile parameters in type 2 diabetic patients. Material & Methods: In a correlational cross-sectional study, 150 type 2 diabetic patients at tertiary care hospital assessed between April and August 2022. HbA1c, fasting blood glucose, and lipid profiles were measured after overnight fasting. Pearson's correlation tested HbA1c's link to lipid profile components. Results: Mean levels of fasting blood glucose, glycated hemoglobin, triglycerides, high-density lipoprotein-cholesterol, and very low-density lipoprotein-cholesterol were similar in males and females. However, females exhibited significantly higher TC (p=0.031) and LDL-C (p=0.018) than males among type 2 diabetes patients. HbA1c strongly correlated with FBG (r=0.684), and glycated hemoglobin displayed a notable positive correlation with total cholesterol (r=0.174). Conclusion: Notably, HbA1c's positive correlation with lipid profiles, particularly TC, implies its potential as a predictor for dyslipidemia alongside glycemic control.

 

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