Sensory neuronopathies constitute a specific subgroup of peripheral neuropathies characterized by primary and selective dorsal root ganglia neuronal destruction. In immune-mediated Sensory neuronopathies, most available data support the concept of direct inflammatory damage to dorsal root ganglia neurons mediated by CD8 T lymphocytes. Large myelinated fibers that convey sense position and vibration are predominantly damaged in Sensory neuronopathies, leads to gait ataxia and widespread arreflexia. Nerve conduction studies are the most useful tests in the evaluation of suspected Sensory neuronopathies. Nerve conduction studies classically show a sensory neuropathy without a distal worsening gradient towards the legs. Sensory nerve conduction studies reveal widespread reduction of sensory action potential amplitudes combined with normal conduction velocity. Here, we describe a clinical case of 74-year-old man, presented with both immune mediated sensory axonal polyneuropathy and elevated prostate specific antigen levels.