Background and Aim: Dysphagia is aclinical condition responsible for substantial morbidity and mortality, especially in elderly population. It has various causes, both benign and malignant. Owing to limited data from Indian population, this study was undertaken to evaluate the clinical profile and various etiologies of dysphagia. Methods: A prospective study was conducted on 213 patients presenting with dysphagia in Department of Gastroenterology, Mahatma Gandhi Medical College & Hospital, Jaipur from September 2022-23. Detailed history, general and systemic examination, endoscopy and guided biopsy and radiological investigations were done. Patients with oropharyngeal or neurological cause of dysphagia were excluded. Results: The mean age of patients was 57.6 years, with the male: female ratio being 1.76:1. 32.39% (n=69)patients had malignant etiology, with mean age of 63.3 years, and 67.61% (n=144) had benign etiology, with mean age of 49 years. Of the malignant cases, 2 (2.89%) patients had gastric cardia adenocarcinoma, 16 (23.18%) had adenocarcinoma of esophagus and 51(73.91%) had squamous cell carcinoma (SCC) of esophagus, lower 1/3^rd of esophagus being the most common site of malignancy. Of the benign etiology, most common cause was esophagitis due to gastro-esophageal reflux seen in 60 patients (28.16%), followed by esophageal ulcer in 12 (5.63%), achalasia in 12 (5.63%), corrosive stricture in 8 (3.75%), peptic stricture in 7 (3.28%), esophageal ring in 6 (2.8%) and, hiatus hernia in 6 patients (2.8%). Conclusion: Dysphagia has a variety of causes. Detailed history and examination followed by endoscopy and radiological evaluation are the key to diagnosis.