Background: Research is a systematic process that helps acquire new knowledge, science, or invention using standard guidelines. An improved understanding of scientific principles and methods is necessary for conducting research. The students should be acquainted with the research methods, enabling them as future doctors to practice evidence-based medicine in patient care. Aim: To assess and compare the knowledge, attitude, and practice towards scientific research among dental students in Kanpur city: Materials and Methods: We conducted a cross-sectional study of 121 undergraduate and postgraduate dental students using a convenience sampling method at a dental college. We used a validated self-report questionnaire to collect data and assess the knowledge, attitude, and practice toward scientific research. "Statistical Package for the Social Sciences is used to analyzed the data" (SPSS) version 23.0 for Windows Data were analyzed by using Chi-Square Test. statistically significant for a value of p≤0.05, were considered Results: Out of 121 participants, 45 (37.2%) were male and 76(62.8%) female students respectively. Subjects, stratified according to year of study, included students in the third year=25 (20.7%); final year=26 (21.5%); Intern=29 (24.0%); postgraduate=41(33.9%). The mean and standard of the knowledge score were 3.46±1.723, 83.5 % had a positive attitude 57.02% had practised scientific research. Conclusion: A high level of research knowledge was found among dental students. Attitude toward research was found to be positive among students. A low level of practice towards scientific research was seen.