People’s life changed drastically with the change in technology.  Internet is one of them which is connecting the global communities through which new ideas, knowledge being shared more easily than before.  Introduction of Smart Phones have made internet more accessible round the clock.  This has led to higher usage of Mobile Phones, especially in adolescent population.  Nomophobia means, ‘No Mobile Phobia’, feeling of missing out.  Nomophobia is indicating danger to the larger part of population.  Adolescents with Nomophobia experiences anxiety issues, impulsivity, sleep disorders, irritability, impacts learning and attention in class room, obsessions and compulsions and effects their eating habits and physical activity.  A systematic review of the literature in done to explore the effects of Nomophobia on adolescent population.  Effects of Nomophobia has been discussed in the research paper along with future directions of research and interventions that can help overcome Nomophobia.