Plants are great source of natural dyes. These natural dyes are yielded by many plant part such as leaves, flowers, roots, seeds and sometimes microorganisms also like algae, fungi etc. These dyes are rich organic sources of printing paper and fibres also. These extracted materials are responsible for their therapeutic and curative properties also due to presence of many bio compounds in it. Natural dyes are curative and commercial also. They have many pharmacological efficiency like antimicrobial, antioxidant, Ameliorative activity, Hepatoprotective activity, no tropic activity, Analgesic activity, antiviral, anticancer, anti-inflammatory etc. These natural dyes are extracted by many extraction methods such as simple aqueous methods, alcoholic or solvent extraction method, complicated solvent systems, supercritical fluid extraction, Microwave or Ultrasonic extraction, Enzymatic extraction, fermentation extraction those are use to isolate pigments from plant parts. Characterisation of dye is main step to show the affinity of dye on its fibre. Extracted dyes are characterised by many parameters like uv-vis spectroscopy, FTIR, HPCL, GCMS, NMR techniques. So, this review revails the pharmacological and economical perspective of natural extracted dye which is useful in medical and commercial industry in the globe.