The purpose of the present study was to find out the Effect of Ladder Training, Plyometric Training and Combined Training on Agility Performance of Inter Collegiate Male Athletes.  For this study, sixty (N=60) athletes who was participated in Anna University Erode Zone inter collegiate Athletic meet in the event of sprinting was randomly selected as subjects. Their age ranged from  18 to 21 years. The subjects were assigned at random into four groups of fifteen each (n=15).  Group-I underwent Ladder training, Group-II underwent Plyometric training, Group-III underwent combined Ladder training and Plyometric training and Group-IV acted as Control.  The age group of the subjects ranged from 18 to 21 years.  The dependent variables selected for this study was Agility. Agility was assessed by 4x10 meter shuttle run test. All the subjects were tested prior to and immediately after the Experimental period on the selected dependent variables. The data obtained from the experimental groups before and after the experimental period were statistically analyzed with dependent  ‘t’-test and Analysis of covariance (ANCOVA). Whenever the ‘F’ ratio for adjusted post-test means was found to be significant, the Scheffe’s test was applied as post-hoc test to determine the paired mean differences. The level of confidence was fixed at 0.05 level for all the cases.   The results of the study showed that the experimental groups namely, Ladder Training group, Plyometric Training group and Combined Ladder Training and Plyometric Training group had significantly improved in Agility.