Dexmedetomidine is an easily adaptable anesthetic agent that can be used in a wide range of perioperative procedures with distinct sedative, analgesic, and sympatholytic effects. Significant benefits can be gained in the perioperative care of surgical patients, especially those with cardiovascular concerns or a history of opioid use, because of its capacity to provide arousable sedation, lower opioid doses, and preserve hemodynamic stability. Dexmedetomidine's clinical relevance is further expanded by its neuroprotective properties, particularly in neurosurgery and trauma settings. Although it is usually well accepted, its usage requires close observation to prevent adverse effects including bradycardia and hypotension. Thus, Dexmedetomidine is a useful addition to the anesthesiologist's armamentarium for incorporation into perioperative care procedures.