Lifespan is influenced by a complex interplay of genetic, environmental, and lifestyle factors, including susceptibility to diseases and survival mechanisms. Early nutritional interventions, such as, the use of food additives, herbal remedies, and mineral supplements, play a pivotal role in shaping growth, survival, and aging outcomes. This study investigated the ameliorative effect of Pomegranate Juice (PJ) a nutrient-rich "Pathya" fruit symbolizing life, health, and longevity against Potassium Bromate (KBrO3) induced toxicity on lifespan using Drosophila melanogaster as a model organism. KBrO3, a widely used as food additive and a major water disinfection by-product, was examined for its impact on lifespan. The experiment consisted of four groups: Group I (Control), Group II (20 mM KBrO3), Group III (Pomegranate Juice), and Group IV (combination of PJ + 20 mM KBrO3), with each group comprising 3 replicates of twenty flies. Results revealed a significant difference in lifespan in KBrO3 treated flies, with reduction of 73% in males and 68% in females as compared to the control. Remarkably, administration of PJ improved longevity by 55% in males and 51% in females exposed to KBrO3, highlighting its protective effect. These findings underscore the potential of PJ in promoting longevity, and improving the quality of life. The observed toxicity of KBrO3 on lifespan suggests its avoidance as a food additive and raises concerns about potential risks to human health if KBrO3 is used in any application.