This study explored working capital management and performance of listed manufacturing firms: an evidence from West Africa. Data employed in this study were generated from secondary source; the dependent variables for this study were return on capital employed and return on equity; while the explanatory variables were mainly, average receivables period, average payment period, and inventory turnover period, alongside firm size as control variable. The study spanned through a period of 11 years (2012-2022). Forty (40) listed manufacturing firms in West Africa were purposively selected for this study. The data generated for this study were analyzed using descriptive analysis, correlation analysis, pooled OLS estimator, fixed effect estimator and random effect estimator. In addition, post estimation test (F-test and Hausma test) were conducted. The findings of this study revealed that, average payable period has significant positive effect on return on capital employed of selected listed manufacturing firms in West Africa, while average receivable period and inventory turnover have insignificant negative effect on return on capital employed. Additionally, the results of the study revealed that, average receivable period and inventory have insignificant negative effect on return on equity of selected listed manufacturing firms in West Africa, while average payable period has insignificant positive effect on return on equity. In line with the findings of this study, the study concluded that, working capital management significantly affects return on capital employed, but only when average payable period is considered. Furthermore, this study concluded that working capital management has insignificant effect on return on equity of quoted manufacturing firms in West Africa.