The burden of cancer continues to rise globally, with low- and middle-income countries (LMICs) like India witnessing disproportionate morbidity and mortality due to late diagnosis and limited preventive services. In this context, the emergence of a new clinical nursing role—the Cancer Control Nurse (CCN) or Preventive Oncology Nurse Specialist—offers a transformative approach to strengthen cancer prevention, screening, health promotion, and early detection at the population level. This article explores the scope, competencies, training needs, and impact of this specialized role, particularly in the Indian setting, while advocating for formal recognition within national cancer control frameworks. The integration of CCNs into multidisciplinary oncology teams has the potential to reduce cancer incidence, improve early detection, and facilitate continuity of care across prevention, screening, and treatment pathways.