Background: Episodes of worsening symptoms in individuals with chronic obstructive pulmonary disease (COPD), known as acute exacerbations of COPD (AECOPD), lead to substantial illness and death. Exacerbations are infrequent in the early stages of COPD and become more prevalent in cases with moderate-to-severe illness. The objectives of our study are to assess the DECAF score among patients with AECOPD, to assess the BAP-65 score among patients with AECOPD, to evaluate the ability of these scores for prediction of mortality among these patients and to assess the correlation between the DECAF score and BAP-65 score. Methods: This prospective observational study was done in the department of pulmonology. Patients with diagnosis of acute exacerbation of chronic obstructive pulmonary disease, age more than 35 years were included in the study. They were evaluated and DECAF score and BAP-65 scores were calculated and analyzed. Results: The mean ± SD age of the study population was 64.68±9.71 years, consisting of 83 (82.17%) males and 18 (17.82%) females. A total of 14 deaths occurred throughout the designated study period. Mean (SD) DECAF score was found to be 1.01 (0.92) among patients who recovered and 3.74 (1.4) among patients who expired. Mean (SD) BAP – 65 class was found to be 1.92 (1) among patients who recovered and 4.28 (0.91) among patients who expired. DECAF score has a sensitivity of 78.57% and specificity of 93.1%. BAP-65 class has a sensitivity of 71.42% and specificity of 94.25%.Conclusion: Both the DECAF and BAP-65 scores are equally effective indicators of mortality.